Who is your patient? (Disease or Health status, age, race, sex)
What do you plan to do for the patient? (Specific tests, therapies, medications)
What is the alternative to your plan? (ie. No treatment, different type of treatment, etc.)
What outcome do you seek? (Less symptoms, no symptoms, full health, etc.)
Note: To minimize confirmation bias in search results, it is typically recommended to exclude outcome-related search terms from your literature search.
What is the time frame? (This element is not always included.)